Soluble brain proteins in dialysis encephalopathy

Soluble brain proteins were analyzed regionally in a case of dialysis encephalopathy and compared to the findings in patients dying from uncomplicated uremia and acute myocardial infarction. Sixteen individual proteins were quantitated and the results may indicate that dialysis encephalopathy is accompanied by defects in the blood-brain barrier. However, such a postulated does not explain why certain proteins (gamma-trace protein) occur at very low concentrations in dialysis encephalopathy.