Myoglobinemia in Duchenne muscular dystrophy carriers

We have carried out serum assays for myoglobin in parallel with the determination of serum CPK activity to assess its usefulness in raising the detectability rate of Duchenne muscular dystrophy carriers. Of the 14 carriers, ten (71.4%) had high serum levels of myoglobin and nine (64.3%) showed increased serum CPK levels. Either parameter revealed elevation in 11 (78.6%) of the 14 cases studied. Serum myoglobin determination is of noticeable value in the detection of Duchenne muscular dystrophy carriers.