Perianal apocrine gland adenoma

A 59-year-old man had a pedunculate perianal tumor initially thought to be a condyloma acuminatum. Since it failed to respond to topical podophyllum resin, the growth was excised and found to be an apocrine gland tumor. Histological features included a duct extending from the surface epidermis to multiple tubules, which led to cystic spaces with papillary projections of columnar epithelium. Decapitation secretion and fibrous stromal proliferation were prominent. The clinical and histological similarities to other apocrine gland adenomas are briefly presented.