[Relationship between the structure and clinical course of chondrosarcomas]

The association between histological structure of chondrosarcomas and their clinical course was studied on the material of 138 clinico-morphological observations. The scheme of O'Neal and Ackerman extended and supplemented by S. I. Lipkin was used to determine the degree of morphological maturity of chondrosarcomas. By the degree of maturity the tumours were divided into 3 groups. No relationship between the rate of recurrence and the degree of maturity was observed. On the contrary, the dependence of metastasizing on the maturity of tumor was statistically significant. Difference in the survival among patients with chondrosarcomas of the I, II, and III degree of maturity was quite significant, particularly in the period of 5-9 years after the establishment of the diagnosis and surgical treatment.