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Updated: Aug 7, 2026
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A Reversible, Non-invasive Method for Airway Resistance Measurements and Bronchoalveolar Lavage Fluid Sampling in Mice
Published on: April 14, 2010
[Reproducibility of bronchial provocative testing in bronchitis (author's transl)]
Zeitschrift Fur Erkrankungen Der Atmungsorgane
|January 1, 1978
Summary
Bronchial hyperreactivity often fluctuates in patients with chronic lung disease, with only 17.5% showing constant reactivity. Bronchial provocative testing is valuable but requires clinical correlation for accurate interpretation.
Area of Science:
- Pulmonology
- Respiratory Medicine
- Clinical Physiology
Context:
- Follow-up study of 40 subjects with chronic nonspecific lung disease.
- All subjects exhibited bronchial hyperreactivity at baseline.
- Longitudinal assessment of bronchial reactivity over time.
Purpose:
- To evaluate the variability of bronchial reactivity in patients with chronic lung disease.
- To assess the correlation between bronchial reactivity test results and clinical symptoms.
- To determine the clinical utility and interpretation guidelines for bronchial provocative testing.
Summary:
- Only 17.5% of subjects demonstrated constant bronchial hyperreactivity throughout the observation period.
- A significant correlation was observed between test results and patient complaints (72% in chronic bronchitis, 65.2% in other subjects).
- Seasonal variations did not strongly influence bronchial reactivity.
Impact:
- Bronchial provocative testing is a valuable tool for verifying obstructive complaints.
- Test results necessitate integration with clinical data for accurate interpretation.
- Reproducibility and clinical agreement are crucial for expert opinions and compensation decisions.
