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Is non-specific cross-reacting antigen a marker on the surface of human basophils?
Annales D'Immunologie
|November 1, 1977
Abstract:
Leucocytes challenged with anti-NCA serum (non-specific cross-reacting antigen) can release histamine. This release is Ca++, glucose and temperature dependent as usually described for basophils. Only half of the subjects whose basophils can release histamine when challenged with anti-IgE serum are also able to release histamine with anti-NCA serum. There is no cross-reaction between IgE and anti-NCA serum or between NCA and anti-IgE serum. So it seems likely that NCA might be a marker on the surface of some human basophils.