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Related Experiment Videos

Sleep apnea in acromegaly

B J Mezon, P West, J P MaClean

    The American Journal of Medicine
    |October 1, 1980
    PubMed
    Summary

    Acromegaly can cause severe sleep apnea due to tongue enlargement obstructing the airway. Tracheostomy resolved somnolence, highlighting the link between acromegaly, airway obstruction, and sleep disruption.

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    Area of Science:

    • Endocrinology
    • Sleep Medicine
    • Otolaryngology

    Background:

    • Acromegaly, a disorder of excess growth hormone, can lead to upper airway obstruction.
    • Sleep apnea syndrome is associated with upper airway obstruction from various causes.

    Observation:

    • A somnolent patient with acromegaly was studied to document sleep apnea syndrome.
    • Nocturnal endoscopy revealed periodic pharyngeal airway obstruction caused by tongue enlargement during sleep.

    Findings:

    • The patient's sleep apnea was directly linked to the tongue bulging into the pharynx.
    • Tracheostomy effectively resolved the patient's somnolence and likely the airway obstruction.

    Implications:

    • Upper airway obstruction in acromegaly can lead to severe hypoxemia and disrupted sleep.
    • This case underscores the importance of evaluating for sleep apnea in acromegaly patients with airway symptoms.