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[Metabolites of bupivacaine in man (author's transl)]
Der Anaesthesist
|April 1, 1980
Abstract:
Following continuous epidural anaesthesia, the urine volumes of patients were collected. By gas-chromatographic analysis 6 metabolites of bupivacaine were identified: 1. Desbutylbupivacaine; 2. 3'-Hydroxy-bupivacaine; 3. N-Butyl-pipecolyl-2-amide; 4. and 5. monohydroxylated isomeres on the piperidine ring; 6. 4'-Hydroxy-bupivacaine.