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Measurement of plasma catecholamines by high-performance liquid chromatography with electrochemical detection in
J Zimmermann1, R Dennhardt, H J Gramm
1Department of Anesthesiology and Critical Care Medicine, Steglitz Medical Center, Free University Berlin, Germany.
Journal of Chromatography
|June 14, 1991
Abstract:
A procedure for the determination of plasma catecholamine concentrations in critical care patients after dobutamine infusion is presented. A modified chromatographic system is required with an additional washing procedure to achieve maximum sensitivity and stable chromatographic conditions. The influence of storage time on the catecholamine concentrations of plasma samples is reported in detail. A time-dependent decrease in catecholamine concentrations of up to 12 and 39% was found within two and ten months, respectively.