[Bromsulphalein dynamic tests in cholelithias patients before and after long-term treatment with chenodeoxycholic...

The BSP loading and continuous infusion tests were performed in 31 patients with cholesterol gallstones before and after long-term (6-12 months) treatment with chenodeoxycholic acid. The following parameters were evaluated: 45th minute retention percentage, plasma disappearance rate during the first 16 minutes, compartmental transfer rates, transport maximum and storage. Our results, according to previous findings after short-term treatment, indicate that no cholestatic effects seem to be induced after long-term treatment with chenodeoxycholic acid.