Related Experiment Video
Updated: Aug 15, 2026
13:09
Mass Spectrometric Analysis of Glycosphingolipid Antigens
Published on: April 16, 2013
Improved method to determine lipid bound sialic acid in plasma or serum
Research Communications in Chemical Pathology and Pharmacology
|October 1, 1980
Summary
A new, simplified method accurately measures lipid-bound sialic acid in plasma and serum. This improved technique uses smaller sample volumes, offering comparable results to previous methods.
Area of Science:
- Biochemistry
- Clinical Chemistry
- Analytical Chemistry
Background:
- Sialic acids are crucial components of glycoproteins and glycolipids.
- Accurate measurement of lipid-bound sialic acid in biological fluids is important for diagnostics.
Purpose of the Study:
- To present an improved, simplified method for determining lipid-bound sialic acid in human plasma or serum.
- To validate the accuracy and efficiency of the new method compared to existing procedures.
Main Methods:
- The study details a refined analytical procedure for lipid-bound sialic acid determination.
- The improved method requires significantly smaller sample volumes (44.7 lambda).
Main Results:
- The simplified method yields results that are in agreement with the earlier, more complex procedure.
- The new method demonstrates comparable accuracy and reliability with reduced sample input.
Conclusions:
- The improved method offers a more efficient and accessible approach for quantifying lipid-bound sialic acid.
- This streamlined technique is suitable for routine clinical and research applications requiring lipid-bound sialic acid analysis.
