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Related Experiment Videos

Two cocaine-induced fatalities

L R Bednarczyk, E A Gressmann, R L Wymer

    Journal of Analytical Toxicology
    |September 1, 1980
    PubMed
    Summary

    Two deaths linked to cocaine use are detailed. One involved intravenous injection, while the other resulted from ruptured drug-filled balloons in the gastrointestinal tract, highlighting diverse routes of fatal cocaine exposure.

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    Area of Science:

    • Forensic Toxicology
    • Analytical Chemistry

    Background:

    • Cocaine remains a significant drug of abuse with potential for fatal outcomes.
    • Understanding routes of administration and associated toxicological findings is crucial for forensic investigations.

    Observation:

    • Case 1: Fatalities associated with intravenous cocaine injection.
    • Case 2: Fatal outcome due to rupture of cocaine-filled balloons within the lower gastrointestinal tract during smuggling.
    • Toxicological analysis of blood, tissue, and drug material was performed.

    Findings:

    • Quantification of cocaine concentrations in biological samples and illicit material.
    • Identification and quantification of adulterants present in the smuggled cocaine.
    • Gas chromatography with a nitrogen-phosphorous detector was utilized for precise analysis.

    Implications:

    • Demonstrates the lethal potential of cocaine through various administration routes, including concealment.
    • Highlights the importance of comprehensive toxicological analysis in post-mortem investigations.
    • Provides data on cocaine purity and adulterant profiles in forensic casework.

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