[Animal experimental testing of the synthetic skin substitute SYSpur-derm]

This publication represents a contribution for the experimental investigation of a suitable skin substitute for temporary covering of vast burns. The synthetic skin substitute SYSpur-derm is a bilaminar polyurethane foam substance. It was tested in the experimental animal pig on skin lesions after third-degree burn and necrectomy. A clean regularly arranged and good vascular granulation tissue was macroscopically and histologically visible on the sixth to the eight day. So favourable conditions were given for the healing up of auto-transplants and it epithelialised partially spontaneously. SYSpur-derm answers the demands on a temporary skin substitute. The synthetic skin substitute offers advantages with regard to the permanent availability, the storage and application, the immunologic inactivity, the sterilisation, and the relatively low cost in face of other materials.