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[Cardiovascular involvement in Behçet's disease. (author's transl)]
Annales De Dermatologie Et De Venereologie
|August 1, 1980
Summary
Behçet disease patients with vascular issues benefited from anticoagulation therapy, showing low relapse rates. This suggests routine anticoagulation or antiplatelet treatment is advisable for managing vascular complications in Behçet disease.
Area of Science:
- Cardiovascular Medicine
- Rheumatology
- Hematology
Context:
- Behçet disease is a rare multisystem inflammatory disorder.
- Vascular manifestations are a significant cause of morbidity and mortality in Behçet disease.
Purpose:
- To evaluate the efficacy of anticoagulation and corticosteroid therapy in managing vascular manifestations of Behçet disease.
- To assess the relapse rates and long-term outcomes in patients treated with anticoagulation.
Summary:
- The study reviewed 35 Behçet disease cases with 16 vascular events, including venous thrombosis, vena cava obstruction, femoral aneurysm, pulmonary artery thrombosis, pericarditis, and myocardial infarction.
- All patients received corticosteroids and anticoagulation therapy.
- Follow-up over 5-36 months showed only 5 relapses within the first five months, indicating treatment effectiveness.
Impact:
- The findings support the routine use of anticoagulation or antiplatelet therapy for preventing and managing vascular complications in Behçet disease.
- This approach may reduce the risk of recurrent thrombotic events and improve patient outcomes.