[Functional state of the gastrin-producing cells in duodenal ulcer patients]

Electron microscopic and specific immunofluorescent studies revealed enhanced hormonal activity of the antral part of the stomach manifested in hyperplasia of gastrin-producing cells in patients with duodenal ulcer. A relationship between the level of stimulated gastric secretion, number of gastrin-producing cells and their functional activity was established. No correlation was found between the values of acidity and levels of basal and stimulated gastrin or the dependence of the latter parameters on the number and functional activity of gastrin-producing cells.