Related Experiment Videos
Extrapolation to man of pharmacological results obtained on animals
Journal of the South African Veterinary Association
|September 1, 1978
Abstract:
Drug development relies on the assumption of a high degree of correlation between the effects of drugs in animals and man. While a good correlation exists as far as the pharmacodynamic action of the drug is concerned it is usually the unpredictable pharmacokinetic properties of the drug responsible for obscuring proper correlations.