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Effect of alpha, alpha, alpha-trifluoro-2-methyl-4'-nitro-m-lactotoluidide (Sch 16423) on serum testosterone and LH
Journal of Reproduction and Fertility
|January 1, 1981
Abstract:
Administration of Sch 16423 to intact male rats (5 mg/day s.c. for 7 days) resulted in a rapid and dramatic rise in the serum concentrations of LH and testosterone. This suggests that this metabolite of flutamide is the active antiandrogenic agent.