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Pigmented villonodular synovitis. A follow-up study

R Donde, J Funding

    Scandinavian Journal of Rheumatology
    |January 1, 1980
    PubMed
    Summary
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    Pigmented villonodular synovitis (PVS) outcomes were studied in 25 patients. Localized PVS cases showed full recovery, while diffuse PVS often resulted in impaired knee mobility.

    Area of Science:

    • Orthopedics
    • Pathology

    Background:

    • Pigmented villonodular synovitis (PVS) is a rare condition affecting the synovium.
    • Long-term outcomes of PVS, particularly in the knee, require further elucidation.

    Purpose of the Study:

    • To evaluate the long-term clinical outcomes of patients diagnosed with pigmented villonodular synovitis (PVS).
    • To differentiate the prognosis based on the localized or diffuse nature of PVS affecting the knee joint.

    Main Methods:

    • Retrospective review of 25 patients diagnosed with PVS between 1950 and 1976.
    • Follow-up examinations conducted 2-28 years post-diagnosis for 22 patients.
    • Classification of knee joint PVS into localized and diffuse types based on intraoperative findings.

    Main Results:

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    • Three patients with localized tendon sheath PVS treated by excision were symptom-free.
    • Of 19 patients with unilateral knee PVS, 6 localized cases had normal knee mobility post-treatment.
    • 13 diffuse knee PVS cases exhibited varying degrees of impaired knee mobility at follow-up.

    Conclusions:

    • Localized pigmented villonodular synovitis (PVS), especially in tendon sheaths and localized knee forms, has a favorable prognosis with complete recovery.
    • Diffuse PVS affecting the knee joint is associated with a higher likelihood of persistent functional impairment and reduced mobility.