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Effect of indomethacin on water intake of the rat

G Feuerstein, M Krausz, Y Gutman

    Pharmacology, Biochemistry, and Behavior
    |December 1, 1978
    PubMed

    Abstract:

    Indomethacin stimulated water intake in intact rats. This effect could also be demonstrated in bilaterally ureteral ligated rats, but it was totally abolished after bilateral nephrectomy. It is suggested that the stimulatory effect of indomathacin on water consumption is mediated by a renal factor.

    Keywords:
    indomethacin effectsrenal drug mediationrat water intakepharmacology of drinking behavior

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