Inhibition of bone marrow cell proliferation and DNA replication induced by chloramphenicol

|January 1, 1980

Abstract:

The effect of CAP on proliferations of bone marow cells from unirradiated and irradiated (4.78 Gy) C57BL/10 mice was investigated by 3H-dTh incorporation into DNA of individual cells using autoradiography. CAP was administered from day 7 to day 10 after irradiation. CAP decreases the rate of entry of cells into S phase and the rate of 3H-dTh incorporation into DNA during replication. Cells of the erythropoietic series are mainly involved in this decrease. CAP has roughly the same inhibitory effect on unirradiated and irradiated cell populations.

Related Concept Videos

Articles linked to this work by shared authors, journal, and citation graph.

Formation of Layered Proton-Conducting Zirconium and Titanium Organophosphonates by Topotactic Reaction: Physicochemical Properties, Proton Dynamics, and Atomic-Resolution Structure.

Inorganic chemistry·2019

Related Experiment Videos

Inhibition of bone marrow cell proliferation and DNA replication induced by chloramphenicol

Related Concept Videos

Formation of Layered Proton-Conducting Zirconium and Titanium Organophosphonates by Topotactic Reaction: Physicochemical Properties, Proton Dynamics, and Atomic-Resolution Structure.

Hematopoiesis in 5-fluorouracil-treated adenosine A(3) receptor knock-out mice.

Erythropoiesis- and thrombopoiesis-characterizing parameters in adenosine A3 receptor knock-out mice.

IB-MECA, an adenosine A(3) receptor agonist, does not influence survival of lethally γ-irradiated mice.

Comparison of different reconstruction algorithms for three-dimensional ultrasound imaging in a neurosurgical setting.

Expression of mRNA for adenosine A(1), A(2a), A(2b), and A(3) receptors in HL-60 cells: dependence on cell cycle phases.

Engineered Bacteriophages in Cancer Immunotherapy: Emerging Concepts and Potential Integration with CAR-T Cell Therapy.

MiR-335-3p Alleviates Adipogenesis and Inflammation in Bone Marrow-Derived Mesenchymal Stem Cells in Osteoporotic Fractures.

Research on the Diagnostic Potential of miR-383-5p in Rheumatoid Arthritis.

The Predictive Value of NLRP3-Mediated Inflammatory Factor Production for Abnormal Liver Function in Pregnant Women with Hepatitis B.

Mechanism Study and Analysis of Correlation between miR-409-3p and Post-Stroke Cognitive Impairment.

Correlation between circ_0092576 and Arterial Stenosis Severity and Inflammatory Status in Patients with Coronary Heart Disease and Its Clinical Value.

Related Experiment Videos

Inhibition of bone marrow cell proliferation and DNA replication induced by chloramphenicol

Abstract:

Related Concept Videos

Related Articles