Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Outward pressure within erythrocytes

A Porath-Füredi, A Levitzki

    Israel Journal of Medical Sciences
    |January 1, 1981
    PubMed
    Summary
    This summary is machine-generated.

    Human erythrocyte osmotic pressure is higher than plasma, indicating a significant intracellular fluid balance mechanism. This osmotic pressure difference is maintained by concentrated intracellular proteins and membrane pressure.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Targeting colorectal cancer via its microenvironment by inhibiting IGF-1 receptor-insulin receptor substrate and STAT3 signaling.

    Oncogene·2015
    Same author

    Targeting melanoma with NT157 by blocking Stat3 and IGF1R signaling.

    Oncogene·2015
    Same author

    Status of p53 in human cancer cells does not predict efficacy of CHK1 kinase inhibitors combined with chemotherapeutic agents.

    Oncogene·2010
    Same author

    Cisplatin induces PKB/Akt activation and p38(MAPK) phosphorylation of the EGF receptor.

    Oncogene·2006
    Same author

    Preclinical analysis of the analinoquinazoline AG1478, a specific small molecule inhibitor of EGF receptor tyrosine kinase.

    Biochemical pharmacology·2006
    Same author

    The potential of tyrphostins for the therapy of breast cancer.

    Breast disease·2005
    Same journal

    Coronary revascularization versus conservative medical management for preoperative optimization of a patients with documented ischemic heart disease.

    Israel journal of medical sciences·1998
    Same journal

    Primary biliary cirrhosis--association or overlap with other autoimmune diseases.

    Israel journal of medical sciences·1998
    Same journal

    Complementary medicine--the problem and the challenge.

    Israel journal of medical sciences·1998
    Same journal

    Electroencephalography in the evaluation of headache patients: a review.

    Israel journal of medical sciences·1998
    Same journal

    Complementary medicine--a critical review.

    Israel journal of medical sciences·1998
    Same journal

    The Israel Longitudinal Mortality Study--differential mortality in Israel 1983-1992: objectives, materials, methods and preliminary results.

    Israel journal of medical sciences·1998
    See all related articles

    Area of Science:

    • Physiology
    • Biophysics

    Background:

    • Human erythrocytes maintain intracellular fluid balance.
    • Osmotic pressure is a critical factor in cell volume regulation.

    Purpose of the Study:

    • To measure the osmotic pressure difference between human erythrocyte contents and plasma.
    • To investigate the factors contributing to this osmotic pressure difference.

    Main Methods:

    • Osmotic pressure measurement of human erythrocyte contents.
    • Comparison with surrounding plasma osmotic pressure.

    Main Results:

    • Erythrocyte contents exhibit an osmotic pressure 35 mosmol/liter (0.79 atm) higher than plasma.
    • This pressure difference persists under hypotonic conditions, albeit reduced.

    Related Experiment Videos

  • Intracellular proteins demonstrate binding capability for additional ions.

    • Conclusions:

    • A significant osmotic pressure gradient exists between erythrocytes and plasma.
    • This gradient is potentially balanced by membrane inward pressure and plasma osmotic pressure.
    • Intracellular protein's ion-binding capacity may contribute to maintaining osmotic balance.