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[Intestinal absorption in the elderly (author's transl)]

R Weiner, R Matkowitz, R Laue

    Zeitschrift Fur Alternsforschung
    |January 1, 1978
    PubMed
    Summary
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    The "generalized absorption" method reveals age-related changes in D-xylose absorption kinetics. While absorption slows with age, healthy elderly individuals still fully absorb nutrients, with malabsorption often linked to increased comorbidity.

    Area of Science:

    • Gastroenterology
    • Gerontology
    • Nutritional Science

    Context:

    • Intestinal absorption and malabsorption are critical physiological processes.
    • The
    • generalized absorption
    • method allows precise quantification.
    • Age-related changes in absorption kinetics require detailed investigation.

    Purpose:

    • To investigate age-dependent alterations in D-xylose absorption kinetics.
    • To determine the clinical significance of age-related changes in intestinal absorption.
    • To explore the relationship between aging, comorbidity, and malabsorption.

    Summary:

    • First-hand examinations revealed age-dependent alterations in D-xylose absorption kinetics.

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  • Absorption velocity decreases, and the overall absorption process is prolonged in the elderly.
  • Despite slower kinetics, healthy elderly individuals exhibit complete substrate absorption, similar to younger adults.

    • Impact:

    • Physiological absorption restriction in the elderly lacks clinical significance under normal conditions.
    • Increased malabsorption cases in older populations are likely attributable to heightened comorbidity.
    • Findings contribute to understanding age-related digestive health and optimizing care for elderly patients.