[Preparatory isolation of subclasses of high density lipoproteins and features of their composition]

An improved procedure is described for separation of high density lipoproteins /HDLP/ into subfractions using narrow salt gradient with optimal concentration for each subfraction. Lipid and protein composition of the HDLP subfractions obtained was studied. Analysis of the subfractions in persons with various concentration of alpha-cholesterol enabled to conclude that concentration of the HDLP2 was preferably increased in hyperalphalipoproteinemia; in this case protein and lipid compositions of both lipoprotein subfractions were not altered as compared with those in normal alphalipoproteinemia.