Related Experiment Video

Updated: Aug 17, 2026

Induction and Monitoring of Active Delayed Type Hypersensitivity (DTH) in Rats
13:26

Induction and Monitoring of Active Delayed Type Hypersensitivity (DTH) in Rats

Published on: July 19, 2007

Dissociation of delayed-type hypersensitivity from acquired murine resistance to Brucella suis

A Escande, A Cannat, A Serre

    Annales D'Immunologie
    |September 1, 1980
    PubMed

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    Delayed-Type Hypersensitivity (DTH), or Type IV hypersensitivity, is a cell-mediated immune response. It occurs when T cells, rather than antibodies, mediate a reaction to specific antigens. It is characterized by a delayed onset (1-2 days) and involves the recruitment of macrophages to the inflammation site.The initiation of a DTH response begins with the sensitization of T cells. During this phase, which lasts at least 1-2 weeks, antigen-specific T cells are activated, clonally expanded, and...