Pulmonary manifestations of tuberous sclerosis

Lung involvement in tuberous sclerosis is rare. Those patients with lung involvement differ from the usual tuberous sclerosis patient in that they are predominantly women, are of normal intelligence, and are less likely to develop epilepsy. The lung disease is often fatal, with cor pulmonale and pneumothorax as the major causes of death. A review of the radiologic and pathophysiologic findings of the lung process are also presented in the following case report.