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Updated: Aug 15, 2026

Drug-Induced Sleep Endoscopy (DISE) with Target Controlled Infusion (TCI) and Bispectral Analysis in Obstructive Sleep Apnea
Published on: December 6, 2016
Neurocognitive deficits in morbidly obese children with obstructive sleep apnea
S K Rhodes1, K C Shimoda, L R Waid
1Department of Psychiatry and Behavioral Sciences, Medical University of South Carolina, Charleston 29425-0742, USA.
Insights
Morbidly obese children with obstructive sleep apnea showed impaired learning, memory, and vocabulary. Apneic/hypopneic events correlated with poorer cognitive performance in all obese children studied.
Area of Science:
- Pediatric Medicine
- Neuroscience
- Sleep Medicine
Background:
- Obesity is a growing public health concern in children.
- Obstructive sleep apnea (OSA) is common in obese children.
- Cognitive deficits associated with OSA are well-documented in adults.
Purpose of the Study:
- To investigate neurocognitive abilities in morbidly obese children.
- To determine if obstructive sleep apnea (OSA) impacts cognitive function in this population.
- To explore the relationship between OSA severity and cognitive performance.
Main Methods:
- Neurocognitive functions were assessed in 14 morbidly obese children.
- Obstructive sleep apnea (OSA) was diagnosed using polysomnography.
- Cognitive measures included learning, memory, and vocabulary assessments.
Main Results:
- Children with OSA exhibited deficits in learning, memory, and vocabulary.
- These cognitive impairments in OSA patients mirrored findings in adult populations.
- A significant inverse relationship was observed between apneic/hypopneic events and memory/learning performance across all participants.
Conclusions:
- Obstructive sleep apnea (OSA) negatively affects neurocognitive abilities in morbidly obese children.
- Cognitive deficits in obese children with OSA are comparable to those seen in adults.
- The frequency of breathing events during sleep is linked to poorer cognitive outcomes in this vulnerable group.
Abstract:
Neurocognitive abilities were measured in 14 morbidly obese children, five of whom had obstructive sleep apnea as determined by polysomnography. As in adults, children with obstructive sleep apnea had deficits in learning, memory, and vocabulary. Moreover, apneic/hypopneic events were inversely related to memory and learning performance among the entire sample.
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