[Functional activity of a metastatic differentiated carcinoma of the thyroid gland]

In a patient with differentiated thyroid carcinoma of the follicular type after removal of the thyroid gland and nodular secondaries on the neck a functional secondary was detected in the liver by combined whole-body scintigraphy following administration of 131-I and scintigraphy of the liver using 99mTc-colloid, supplemented by scintigraphy of the skeleton following administration of 99mTc-MDP. At first the high thyroglobulin serum level was after repeated radioiodine treatment falsely negative. The author presents a review of cases reported in the literature who suffered from this rare type of secondaries.