[Polymer-containing eyedrops. IV. Microbiological study of eyedrops containing antibiotics]

Authors studied microbiological activities of eye-drops containing neomycin sulphate, gentamicin-sulphate and chloramphenicol, respectively. Effects of viscous eye-drops on Bacillus subtilis were measured by comparing them with resistest disc in the function of the type and concentration of macromolecule, pH and electrolyte content of the solution. It was found that viscosity increasing solution does not have any significant effect on the microbiological activity of the eye-drop in the studied range of concentration. Effectivity of the solution does not change either during storage.