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Contrast-Enhanced Subharmonic Aided Pressure Estimation (SHAPE) Using Ultrasound Imaging with a Focus on Identifying Portal Hypertension
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Hepatic involvement in Osler-Weber-Rendu disease: findings on pulsed and color Doppler sonography

H Naganuma1, H Ishida, M Niizawa

  • 1First Department of Internal Medicine, Akita University School of Medicine, Japan.

AJR. American Journal of Roentgenology
|December 1, 1995
PubMed

Insights

Doppler sonography revealed dilated hepatic arteries with increased flow velocity in Osler-Weber-Rendu disease patients, though microscopic shunts were undetected. Portal vein flow remained normal in these patients.

Area of Science:

  • Vascular imaging
  • Medical diagnostics
  • Hepatology

Background:

  • Osler-Weber-Rendu disease is a genetic disorder affecting blood vessels.
  • Hepatic vasculature hemodynamics can be assessed using Doppler sonography.
  • Understanding vascular changes in Osler-Weber-Rendu disease is crucial for diagnosis and management.

Purpose of the Study:

  • To compare liver vasculature hemodynamics in Osler-Weber-Rendu disease patients versus healthy controls using Doppler sonography.
  • To assess vessel diameter, flow velocity, and shunt presence in hepatic and portal vessels.

Main Methods:

  • Real-time and pulsed Doppler sonography were employed.
  • 10 patients with Osler-Weber-Rendu disease and 25 healthy subjects were studied.
  • Hepatic and portal vein branches, as well as hepatic veins, were analyzed.

Main Results:

  • Hepatic arteries were dilated and tortuous with significantly higher flow velocity in patients (153 cm/sec) compared to controls (65 cm/sec).
  • No significant difference in hepatic artery resistive index or intrahepatic arteriovenous shunts was detected.
  • Arterioportal and portovenous shunts were identified in two patients; portal venous flow was similar between groups.

Conclusions:

  • Doppler sonography indicated hepatic artery dilatation and increased flow velocity in Osler-Weber-Rendu disease, likely due to undetected microscopic arteriovenous shunts.
  • Portal vein hemodynamics were not significantly altered.
  • Doppler sonography effectively identified large intrahepatic shunts.
Abstract

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