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Related Experiment Videos

Gender differences in device therapy for malignant ventricular arrhythmias

H L Horton1, R A Marinchak, S J Rials

  • 1Division of Cardiovascular Diseases, Lankenau Hospital, Wynnewood, Pa, USA.

Archives of Internal Medicine
|November 27, 1995
PubMed
Summary

While initial recommendations and implantation rates for implantable cardioverter-defibrillators were similar, women refused devices more often and were deemed medically ineligible more frequently, leading to fewer women receiving these life-saving devices.

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Area of Science:

  • Cardiology
  • Medical Device Technology
  • Gender Health Disparities

Background:

  • Recent reports suggest gender bias in cardiovascular disease treatment.
  • This study investigates potential gender bias in treating malignant ventricular arrhythmias.

Purpose of the Study:

  • To compare baseline characteristics and treatment modalities for malignant ventricular arrhythmias between men and women.
  • To analyze implantable cardioverter-defibrillator (ICD) implantation rates in relation to gender.

Main Methods:

  • Retrospective chart review of 130 patients evaluated for malignant ventricular arrhythmias (July 1990 - June 1992).
  • Comparison of cardiovascular and clinical parameters, treatment recommendations, and ICD implantation rates between genders.

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Main Results:

  • No significant difference in ICD recommendation or implantation rates between women and men.
  • Women had lower rates of coronary artery disease and myocardial infarction, with higher ejection fractions.
  • Significantly more women refused ICDs or were deemed medically ineligible, resulting in fewer women receiving ICDs despite similar indications.

Conclusions:

  • No gender difference in ICD recommendation or implantation rates was initially observed.
  • Higher refusal and ineligibility rates in women led to fewer ICD implantations compared to men with similar indications.
  • This disparity did not appear to increase short-term mortality.