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Radioactive and non-radioactive lymphocyte proliferation assays for measuring rabies-specific cellular immunity

S Kasempimolporn1, P Chomchey, V Sitprija

  • 1Queen Saovabha Memorial Institute, Thai Red Cross Society, Bangkok, Thailand.

Asian Pacific Journal of Allergy and Immunology
|June 1, 1995
PubMed

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Rabies is a lethal zoonotic disease caused by a single-stranded, negative-sense RNA virus of the Lyssavirus genus, within the family Rhabdoviridae. Its primary mode of transmission to humans is through bites or saliva-contaminated scratches from infected mammals such as dogs, bats, raccoons, or foxes. Transmission can also occur if infectious saliva contacts abraded skin or intact mucous membranes, including the conjunctiva.Viral Entry and Early ReplicationOnce introduced at the bite or scratch...