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Atypical herpetic endotheliitis

S J Bass1, J Sherman, G Panariello

  • 1State University of New York, State College of Optometry, NY 10010, USA.

Journal of the American Optometric Association
|September 1, 1995
PubMed
Summary
This summary is machine-generated.

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Herpetic endotheliitis can affect young adults, presenting as unilateral posterior stromal lesions without epithelial involvement. Early diagnosis and treatment with antivirals and corticosteroids are crucial for managing this condition.

Area of Science:

  • Ophthalmology
  • Infectious Diseases

Background:

  • Presents three cases of young adults (26-40 years) with unilateral posterior stromal lesions and diffuse stromal edema.
  • Absence of prior surgery, trauma, infectious disease, dystrophy, or noxious agent exposure noted.
  • Key atypical features of herpetic disease observed: lack of epithelial involvement and posterior stromal opacification.

Observation:

  • One patient exhibited anterior chamber reaction; none showed epithelial involvement, vascularization, or scarring.
  • Patients displayed a mix of atypical and typical herpetic disease characteristics.
  • Diagnosis of herpetic endotheliitis was established based on clinical presentation.

Findings:

  • Treatment involved a combination of antiviral agents and corticosteroids.

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  • Two out of three patients showed improvement, with varying timelines.
  • One patient experienced a relapse after self-discontinuation of treatment and was lost to follow-up.

    • Implications:

    • Suggests that young patients with unilateral posterior stromal opacification and edema, without epithelial signs, may have herpetic endotheliitis.
    • Highlights the importance of considering herpetic origin in atypical presentations.
    • Underscores the need for consistent treatment adherence for favorable outcomes.