Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

From muscle properties to human performance, using magnetic resonance

K E Conley1, M E Cress, S A Jubrias

  • 1Department of Radiology, University of Washington Medical Center, Seattle, USA.

The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences
|November 1, 1995
PubMed
Summary

Magnetic resonance (MR) imaging and spectroscopy noninvasively assess elderly muscle properties, revealing exercise limitations. These in vivo measurements link muscle structure and energy to functional capacity and daily activities.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Paradoxical embolism after cardiac catheterization.

Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association·2015
Same author

In vivo metabolic spectroscopy identifies deficits in mitochondrial quality and capacity in aging skeletal muscle.

Clinical pharmacology and therapeutics·2014
Same author

Lumbar radiculopathy and intraspinal gas.

Journal of back and musculoskeletal rehabilitation·2014
Same author

The effect of telephone counselling on reducing post-traumatic symptoms after mild traumatic brain injury: a randomised trial.

Journal of neurology, neurosurgery, and psychiatry·2008
Same author

The WeeFIM [R] instrument--a paediatric measure of functional independence to predict longitudinal recovery of paediatric burn patients.

Developmental neurorehabilitation·2007
Same author

Hypoglycemic coma associated with brain infarcts.

Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association·2007

Area of Science:

  • Exercise Physiology
  • Medical Imaging
  • Gerontology

Background:

  • Aging leads to decreased exercise performance in the elderly.
  • Understanding the underlying muscle limitations is crucial for targeted interventions.
  • Noninvasive methods are needed to assess muscle health in older adults.

Purpose of the Study:

  • To demonstrate how muscle properties, assessed noninvasively, can explain exercise limitations in the elderly.
  • To establish magnetic resonance (MR) techniques as tools for evaluating muscle structure and energy metabolism in vivo.
  • To correlate in vivo muscle measurements with functional capacity and everyday activities relevant to the elderly.

Main Methods:

  • Utilizing magnetic resonance (MR) imaging for quantitative morphometric analysis of muscle volume and cross-sectional area.

Related Experiment Videos

  • Employing advanced MR spectroscopy techniques for noninvasive assessment of muscle oxidative, glycolytic, and contractile capacities.
  • Relating MR-derived muscle properties (structural and energetic) to whole-body performance metrics like VO2max.
  • Connecting laboratory findings to functional outcomes in daily life activities such as walking and stair climbing.

    • Main Results:

    • MR imaging accurately and rapidly determines muscle structural parameters (volume, cross-sectional area).
    • MR spectroscopy provides a noninvasive "biopsy" of muscle fiber metabolic capacities (oxidative, glycolytic, contractile).
    • In vivo measured muscle properties correlate with functional capacity and overall exercise performance (e.g., VO2max).

    Conclusions:

    • Noninvasive MR techniques are effective for characterizing elderly muscle structure and energetics.
    • These MR-derived muscle properties are key determinants of exercise performance limitations in older adults.
    • Linking MR measurements to functional capacity and daily activities offers insights into maintaining elderly independence.