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Histopathology of transgenic mouse mammary tumors (a short atlas)

R J Munn1, M Webster, W J Muller

  • 1Department of Pathology, School of Medicine, University of California Davis 95616, USA.

Seminars in Cancer Biology
|June 1, 1995
PubMed

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Mice have long served as models for studying human biology and pathology because of their phylogenetic and physiological similarity with humans. They are also easy to maintain and breed in the laboratory, and hence, many inbred strains are now available for research. Studies on mice have contributed immeasurably to our understanding of cancer biology.
The development of transgenic, knockout, and knock-in mice has led to an exponential increase in their use as model organisms in research,...