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Inside SWISS-2DPAGE database

J C Sanchez1, R D Appel, O Golaz

  • 1Clinical Chemistry Laboratory, University Hospital, Geneva, Switzerland.

Electrophoresis
|July 1, 1995
PubMed
Summary
This summary is machine-generated.

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The SWISS-2DPAGE database offers a unified format for protein information from human samples. This hypermedia database is now accessible via the World-Wide Web (WWW) for broader research use.

Area of Science:

  • Proteomics
  • Bioinformatics
  • Molecular Biology

Background:

  • Established two-dimensional polyacrylamide gel electrophoresis (2-D PAGE) databases exist but sharing has been limited.
  • Recent advancements in computer networks and transfer protocols enable comprehensive database sharing.

Purpose of the Study:

  • To describe the structure and accessibility of the SWISS-2DPAGE database.
  • To provide a uniform and accessible format for protein data derived from human samples.

Main Methods:

  • Development of a hypermedia database structure for 2-D PAGE data.
  • Assembly and description of proteins from human tissues, cells, and body fluids.
  • Integration with World-Wide Web (WWW) accessibility on the ExPASy server.

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Main Results:

  • The SWISS-2DPAGE database structure is detailed.
  • Proteins are cataloged in a standardized format.
  • The database is freely accessible online.

Conclusions:

  • SWISS-2DPAGE facilitates the sharing of comprehensive 2-D PAGE data.
  • Online accessibility through the WWW enhances protein research capabilities.
  • This resource supports the study of human proteomes.