Of mice and mutants: target size and sensitivity

Detection of DNA adducts using a quantitative long PCR technique and the fluorogenic 5' nuclease assay (TaqMan).

Mutation research·2001

Suppression of spontaneous and hydrogen peroxide-induced mutagenesis by the antioxidant ascorbate in mismatch repair-deficient human colon cancer cells.

Carcinogenesis·2001

Use of real-time gene-specific polymerase chain reaction to measure RNA expression of three family members of rat cytochrome P450 4A.

Journal of biochemical and molecular toxicology·2001

Extent of CpG methylation is not proportional to the in vivo spontaneous mutation frequency at transgenic loci in Big Blue rodents.

Mutation research·2001

Specificity of mutations induced by the food-associated heterocyclic amine 2-amino-1-methyl-6-phenylimidazo-[4,5-b]-pyridine in colon cancer cell lines defective in mismatch repair.

Cancer research·2000

Biomarkers of exposure and effect as indicators of potential carcinogenic risk arising from in vivo metabolism of ethylene to ethylene oxide.

Carcinogenesis·2000

The role of KIT mutations in oral melanoma and disease progression: A literature review on early detection and targeted therapy.

Mutation research·2026

Mothers against decapentaplegic homolog 3-activated FAT atypical cadherin 2 regulates programmed death ligand-1 to mediate immune evasion in lung squamous cell carcinoma.

Mutation research·2026

Potential targets and molecular mechanisms of curcumin in treating Laryngeal and Pharyngeal Carcinoma throat cancer based on network pharmacology and bioinformatics analysis.

Mutation research·2026

Non-clonal interphase markers of chromosomal instability in malignancy acquisition and cancer progression.

Mutation research·2026

miR-145-5p induces ferroptosis by targeting Notch2 to suppress melanoma progression.

Mutation research·2026

Monoallelic germline RAD51C, RAD51D, and BRIP1 variants in hereditary cancer testing: Variant spectrum and clinical counselling implications.

Mutation research·2026

Cardiometabolic Effects of Dual GLP-1 and Glucagon Receptor Agonists: A Systematic Review and Meta-analysis of Randomized Controlled Trials.

Diabetes care·2026

Macrophage PABPC4-SPP1 Axis Orchestrates Immunosuppression in Colorectal Cancer.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)·2026

Integrin-Linked Kinase Suppression Reduces SPARC's Effect on Intraocular Pressure and Extracellular Matrix.

Investigative ophthalmology & visual science·2026

Molecular classification and precision therapy in gastric cancer: Current advances and future perspectives (Review).

Oncology reports·2026

Unlocking the potential of microRNA as predictive biomarkers for efficacy and adverse events in immune checkpoint inhibitor therapy (Review).

Molecular medicine reports·2026

Post‑translational modification‑governed immune states in cancer immunity: Biomarker implications for checkpoint competence, tumor visibility and immunotherapy resistance (Review).

International journal of oncology·2026

Related Experiment Videos

Of mice and mutants: target size and sensitivity

Related Concept Videos

Detection of DNA adducts using a quantitative long PCR technique and the fluorogenic 5' nuclease assay (TaqMan).

Suppression of spontaneous and hydrogen peroxide-induced mutagenesis by the antioxidant ascorbate in mismatch repair-deficient human colon cancer cells.

Use of real-time gene-specific polymerase chain reaction to measure RNA expression of three family members of rat cytochrome P450 4A.

Extent of CpG methylation is not proportional to the in vivo spontaneous mutation frequency at transgenic loci in Big Blue rodents.

Specificity of mutations induced by the food-associated heterocyclic amine 2-amino-1-methyl-6-phenylimidazo-[4,5-b]-pyridine in colon cancer cell lines defective in mismatch repair.

Biomarkers of exposure and effect as indicators of potential carcinogenic risk arising from in vivo metabolism of ethylene to ethylene oxide.

The role of KIT mutations in oral melanoma and disease progression: A literature review on early detection and targeted therapy.

Mothers against decapentaplegic homolog 3-activated FAT atypical cadherin 2 regulates programmed death ligand-1 to mediate immune evasion in lung squamous cell carcinoma.

Potential targets and molecular mechanisms of curcumin in treating Laryngeal and Pharyngeal Carcinoma throat cancer based on network pharmacology and bioinformatics analysis.

Non-clonal interphase markers of chromosomal instability in malignancy acquisition and cancer progression.

miR-145-5p induces ferroptosis by targeting Notch2 to suppress melanoma progression.

Monoallelic germline RAD51C, RAD51D, and BRIP1 variants in hereditary cancer testing: Variant spectrum and clinical counselling implications.

Cardiometabolic Effects of Dual GLP-1 and Glucagon Receptor Agonists: A Systematic Review and Meta-analysis of Randomized Controlled Trials.

Macrophage PABPC4-SPP1 Axis Orchestrates Immunosuppression in Colorectal Cancer.

Integrin-Linked Kinase Suppression Reduces SPARC's Effect on Intraocular Pressure and Extracellular Matrix.

Molecular classification and precision therapy in gastric cancer: Current advances and future perspectives (Review).

Unlocking the potential of microRNA as predictive biomarkers for efficacy and adverse events in immune checkpoint inhibitor therapy (Review).

Post‑translational modification‑governed immune states in cancer immunity: Biomarker implications for checkpoint competence, tumor visibility and immunotherapy resistance (Review).

Related Experiment Videos

Of mice and mutants: target size and sensitivity

Related Concept Videos

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