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Related Experiment Videos

The pars defect as a pain source. A histologic study

G A Schneiderman1, R F McLain, M F Hambly

  • 1Northern California Spine and Rehabilitation, Sacramento, USA.

Spine
|August 15, 1995
PubMed
Summary
This summary is machine-generated.

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Nerve endings were found in pars defect tissue from patients with spondylolysis. This suggests the pars defect may cause back pain in some individuals.

Area of Science:

  • Spine surgery
  • Histopathology
  • Pain research

Background:

  • The origin of back pain in spondylolysis is unclear.
  • The pars interarticularis defect is a potential pain generator.

Purpose of the Study:

  • To investigate the presence of nociceptive nerve endings in the pars defect of patients with symptomatic spondylolysis.

Main Methods:

  • Histologic examination of pars defect tissue from six adult patients.
  • Modified gold chloride staining for neural elements.
  • Light microscopy analysis.

Main Results:

  • Neural elements were identified in all examined specimens.
  • Nociceptive free nerve endings were present in all samples.

Related Experiment Videos

  • Varied neural element density observed across specimens.

    • Conclusions:

    • The presence of neural elements, including nociceptive nerve endings, in pars defect tissue indicates a potential source of pain.
    • This finding supports the pars defect as a contributor to back pain in symptomatic spondylolysis.