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Numerical quadruplet code of human cervical carcinoma tissue proteins
1Department of Biology, School of Medicine, University of Zagreb, Croatia.
Abstract:
Proteins were extracted from cervical cancer tissue at 100,000 g supernatant. The four most abundant extracted tissue proteins form a "numerical quadruplet code", by which tissues can be distinguished from each other. Proteins that are specific for cervical cancer were a protein with a relative migration rate of 0.5, obtained by disc-electrophoresis, and a small protein, p 35, obtained by SDS-PAGE. This shows that, in a malignant process, the expression of a new protein may occur or, more probably, an already existing protein is better expressed.
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