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Published on: September 9, 2014
[A method for the isolation of sterile Coombs serum]
Folia Haematologica (Leipzig, Germany : 1928)
|January 1, 1977
Summary
High-titer Coombs serum can now be produced without sterile filtration, preventing quantitative and qualitative losses during production and storage. This new method avoids serum degradation, ensuring higher quality and yield.
Area of Science:
- Immunology
- Biotechnology
Context:
- Sterile filtration and long-term storage of Coombs serum can lead to significant quantitative and qualitative losses.
- Maintaining high-titer serum is crucial for diagnostic and research applications.
Purpose:
- To develop a method for producing high-titer sterile Coombs serum that minimizes or eliminates losses associated with sterile filtration.
- To circumvent the need for sterile filtration in Coombs serum production.
Summary:
- A novel method has been devised to produce high-titer sterile Coombs serum.
- This technique avoids the conventional sterile filtration step, thereby preventing associated serum losses.
- The process ensures the integrity and potency of the Coombs serum.
Impact:
- Reduced reagent costs due to minimized product loss.
- Improved consistency and reliability of Coombs serum for laboratory use.
- Potential for broader application in diagnostics and research where high-quality serum is essential.
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