[Specific ENT involvement in a case of angio-immunoblastic adenopathy (author's transl)]

The authors report the case of a 78 year old man with an unusual localization (soft palate and tonsil) of an angio-immunoblastic lymphadenopathy. Clinically, the syndrome combines fever, a marked change in general condition, multiple lymphadenopathy and skin rash. From a laboratory standpoint, the picture is dominated by polyclonal hypergammaglobulinemia, often associated with a hemolytic anemia. Histologically, only lymphnode biopsy allows the diagnosis to be made, with the following findings: disruption of the normal architecture of the node, marked vascular neogenesis, presence of acidophilic interstitial substance, lympho-plasmo-immunoblastic proliferation. The course is in general rapidly fatal despite corticosteroids and multiple chemotherapy.