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Influence of serotonin on calcium transport in rat liver mitochondria
Biology Bulletin of the Academy of Sciences of the USSR. Akademiia Nauk SSSR
|May 1, 1978
Abstract:
It was shown in experiments in vitro that serotonin, depending on the concentration, has different effects on calcium transport in rat liver mitochondria. In a concentration of 10(-6) M it increases the ability of the mitochondria to bind calcium; in a higher concentration (10(-4) M) serotonin accelerates the release of calcium from the mitochondria. The effect of serotonin is detected at a calcium concentration in sucrose medium of the order of 10(-4) M and is not observed when the mitochondria are incubated in a complete reaction medium.