Refractive corneal surgery with the Draeger rotary microkeratome in human cadaver eyes

Instrumentation for performing a uniform lamellar keratoplasty has been undergoing various stages of refinement. Reliable reproduction and uniform thickness and diameter of lamellar resections is required before lamellar refractive keratoplasty can be considered safe and effective.

The authors used the Draeger rotary microkeratome with mechanical blade advance for lamellar dissections in 61 human cadaver eyes prepared by injecting Swinger-Kornmehl (SK) solution into the anterior chamber to a pressure of 35 to 40 mm Hg and by soaking for 30 minutes in SK solution. Spacer sizes of 0.25 to 0.40 units were utilized using an anterior lamellar disc diameter estimate between 8.0 and 8.5 mm and a stromal lamellar disc diameter estimate between 5.5 and 6.5 mm. Preoperative pachometry, anterior and stromal lamellar disc thicknesses, and anterior and stromal lamellar disc diameters were measured.

The Draeger unit created anterior lamellar thickness between 100 and 268 microns. Stromal lamellar disc thicknesses were consistently between 90 and 161 microns. The continuous, unidirectional, rotary blade and the uniform mechanical advance of the instrument produced a generally uniform bed as evaluated by scanning electron microscopy, although undulations were still present.

The Draeger microkeratome produced regular lamellar dissections; however, predictability of the thickness of the lenticules varied 10% to 20%, and of the diameter, 1.5% to 15%. Predictability improved with experience. This variability may reduce predictability of refractive outcome.