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Successful reversal of neutropenia in Felty's syndrome with recombinant granulocyte colony stimulating factor
M F Choi1, M J Mant, A R Turner
1Department of Medicine, University of Alberta, Canada.
British Journal of Haematology
|March 1, 1994
Abstract:
We report two patients with Felty's syndrome and chronic skin ulcers treated successfully with recombinant granulocyte colony stimulating factor (GCSF). In both cases granulocytes returned to the normal range within days of starting treatment, and their cutaneous ulcers improved. In one patient granulocytes were maintained at normal levels with a regimen of GCSF 3 micrograms/kg twice weekly for 14 months.