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Updated: Oct 15, 2026

An In Vitro Preparation for Eliciting and Recording Feeding Motor Programs with Physiological Movements in Aplysia californica
Published on: December 5, 2012
The nerve rings twice
1Department of Dermatology, Kyoto University Graduate School of Medicine, 54 Shogoin Kawahara-cho, Sakyo-ku, Kyoto 606-8507, Japan; A∗STAR Skin Research Labs (A∗SRL), Skin Research Institute of Singapore (SRIS), and Singapore Immunology Network (SIgN), Agency for Science, Technology and Research (A∗STAR), 8A Biomedical Grove, IMMUNOS Building, Biopolis, Singapore 138648, Singapore.
Abstract:
How does neural activity ignite skin inflammation? In this issue, Chen et al. show that one round of nociceptor activation builds a transient, chemokine CCL2-dependent dendritic cell-rich neighborhood, whereas a second round within the tested 3-12-h range licenses an IL-23-centered program through neuropeptide CGRPα.
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