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Ventricular arrhythmia factors in mitral valve prolapse
D Babuty1, P Cosnay, J C Breuillac
1Service de Cardiologie B, Hôpital Trousseau, Tours, France.
Pacing and Clinical Electrophysiology : PACE
|June 1, 1994
Summary
Ventricular arrhythmias and late potentials are common in mitral valve prolapse (MVP). Older age and mitral regurgitation are linked to these arrhythmias, while signal-averaged ECG can help identify low-risk patients.
Area of Science:
- Cardiology
- Electrophysiology
Background:
- Mitral valve prolapse (MVP) is a common valvular heart disease.
- The risk of ventricular arrhythmias in MVP patients requires further investigation.
Purpose of the Study:
- To determine the prevalence of ventricular arrhythmias and late potentials (LPs) in MVP patients.
- To identify clinical, ECG, and echocardiographic predictors of spontaneous ventricular arrhythmias in MVP.
Main Methods:
- 58 consecutive MVP patients underwent 24-hour ECG, exercise stress tests, signal-averaged ECG, and programmed ventricular stimulation.
- Clinical, ECG, and echocardiographic data were analyzed for correlations with arrhythmias.
Main Results:
- 17.2% had spontaneous nonsustained ventricular tachycardia (NSVT), 44.8% had significant premature ventricular contractions (PVCs), and 22.4% had LPs.
- LPs correlated significantly with spontaneous VT and induced ventricular arrhythmias (P < 0.005).
- Older age and mitral regurgitation were associated with complex ventricular arrhythmias.
Conclusions:
- Complex ventricular arrhythmias and LPs are frequent in MVP.
- Patient age and mitral regurgitation are key factors for ventricular arrhythmias in MVP.
- Absence of LPs on signal-averaged ECG may identify MVP patients without spontaneous VT.