Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Localization of brain function using magnetic resonance imaging

M S Cohen1, S Y Bookheimer

  • 1Dept. of Neurology, UCLA School of Medicine 90024.

Trends in Neurosciences
|July 1, 1994
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Sensory over-responsivity and atypical neural responses to socially relevant stimuli in autism.

Autism research : official journal of the International Society for Autism Research·2024
Same author

Baseline brain function in the preadolescents of the ABCD Study.

Nature neuroscience·2021
Same author

Refining the Definitions of Biochemical and Clinical Cure for Primary Aldosteronism Using the Primary Aldosteronism Surgical Outcome (PASO) Classification System.

World journal of surgery·2017
Same author

Novel C-Terminal Heat Shock Protein 90 Inhibitors (KU711 and Ku757) Are Effective in Targeting Head and Neck Squamous Cell Carcinoma Cancer Stem cells.

Neoplasia (New York, N.Y.)·2017
Same author

Additive effects of oxytocin receptor gene polymorphisms on reward circuitry in youth with autism.

Molecular psychiatry·2016
Same author

Functional connectivity for face processing in individuals with body dysmorphic disorder and anorexia nervosa.

Psychological medicine·2015
Same journal

Emulating the periodic table: A unified list of CNS terms and abbreviations for humans and experimental animals.

Trends in neurosciences·2026
Same journal

From chromatin dynamics to brain disease: Polycomb-Trithorax mechanisms in neurodevelopment.

Trends in neurosciences·2026
Same journal

Striatum regulates the cortex via the basal forebrain cholinergic system: A role for substance P.

Trends in neurosciences·2026
Same journal

A large brain adds new types of neurons: Molecular and functional signatures of spindle neurons in the human neocortex.

Trends in neurosciences·2026
Same journal

Exercise as a regulator of glymphatic function.

Trends in neurosciences·2026
Same journal

The neural basis of laughter.

Trends in neurosciences·2026
See all related articles

Functional MRI (fMRI) detects brain activation by measuring blood oxygenation changes. This non-invasive technique precisely maps brain function with millimeter accuracy and second-level temporal resolution.

Area of Science:

  • Neuroscience
  • Medical Imaging

Background:

  • Functional magnetic resonance imaging (fMRI) relies on detecting signal alterations in brain images.
  • These signal changes are linked to variations in blood oxygenation levels within the venous system.

Purpose of the Study:

  • To explain the underlying principles of functional MRI (fMRI).
  • To highlight the capabilities of fMRI in localizing brain activation.

Main Methods:

  • Acquisition of rapid, successive nuclear magnetic resonance images (MRIs) of the brain.
  • Analysis of signal intensity differences correlating with focal brain activation areas.
  • Relating signal variations to changes in venous blood oxygenation.

Main Results:

  • fMRI enables the localization of functional brain activation with millimeter accuracy.

Related Experiment Videos

  • The method offers a temporal resolution on the order of seconds.
  • Identifies focal areas of brain activation based on hemodynamic responses.

    • Conclusions:

    • Functional MRI (fMRI) is a powerful non-invasive tool for neuroscience research.
    • Despite technical challenges, fMRI is crucial for mapping the human brain's topographical organization.
    • This technique advances our understanding of how the brain functions.