[Experimental studies on the role of lactic acid in pathogenesis of neovascularization]

In order to elucidate the controversies whether lactic acid could be the factor responsible for the initiation of neovascularization, the author examined neovascular response of the vessels of the chicken chorioallantoic membrane after implantation of filter discs soaked with different concentrations of this substance. No neovascularization of the vessels of the membrane was seen after implantation of the discs. The results of the study suggest that lactic acid is not the factor which can stimulate neovascularization.