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The retrocuspid papilla and factor XIIIa: an epidemiologic and histomorphologic study
Scandinavian Journal of Dental Research
|October 1, 1994
Summary
The retrocuspid papilla (RCP) is a rare gingival lesion. Our study identified RCP in over 2000 oral biopsies, highlighting its presence in attached gingiva near mandibular canines.
Area of Science:
- Oral pathology
- Dermatopathology
- Histopathology
Background:
- The retrocuspid papilla (RCP) is an infrequently recognized oral mucosal lesion.
- Previous literature provides limited information on its prevalence and histological characteristics.
Purpose of the Study:
- To investigate the prevalence and histological features of the retrocuspid papilla (RCP).
- To characterize the cellular components and potential pathogenetic role of RCP.
Main Methods:
- Retrospective analysis of clinical findings in 1150 patients.
- Histopathological examination of over 2000 oral mucosal hyperplasia biopsies (1989-1992).
- Immunohistochemical staining using FXIIIa antibody.
Main Results:
- 10 clinically compatible RCP cases found in 1150 patients.
- 15 RCP cases identified in over 2000 biopsies.
- Lesions located in attached gingiva, lingual to mandibular canines, measuring 2-3 mm.
- Histology revealed parakeratinized epithelium, elongated rete pegs, and delicate connective tissue.
- Two histological groups identified based on fibroblast presence; FXIIIa staining showed reactive spindle-shaped cells.
Conclusions:
- Retrocuspid papilla (RCP) is a distinct entity with specific histological features.
- FXIIIa-positive spindle-shaped cells in the connective tissue papillae may play a role in RCP pathogenesis.