[Blood proteinase inhibitors and cathepsin D in diffuse peritonitis]

There were 52 patients with a diffuse peritonitis examined. The level of a proteinases alpha 1-inhibitor, alpha 2-macroglobulin, trypsin inhibitor, cathepsin-D was studied. Results witnesses the high activity of proteinases inhibitors cathepsin-D in the early, postoperative period. The level of alpha 2-macroglobulin and cathepsin-D in an elderly and senile patients approximated to normal values up to the 7-9th day after the operation. The dependence of proteinases inhibitors and cathepsin-D contents from the severity of peritonitis course, the number of interventions done to the patient, and the use of autologous blood photomodifization in the complex of treatment were not revealed.