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The endodermal sinus tumour and clear cell ovarian cancer
1Gynaecological Oncology Unit, Royal Marsden Hospital, London, U.K.
Abstract:
There are similarities between clear cell epithelial ovarian carcinoma and endodermal sinus tumours. Apart from the morphological and clinical characteristics there are immunohistochemical markers of value in differentiating these 2 tumours and the detection of a raised serum AFP is characteristic of endodermal sinus tumours. These 3 cases we describe show the fallibility of the classical differentiating criteria between these two tumours.